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AllergiesasthmaEvidence 3
rs6475448 · MLLT3
Risk allele: A
Risk-Allele Phenotype
MLLT3 rs6475448 — associated with altered response to montelukast therapy in asthma, specifically a change in FEV1 (forced expiratory volume in 1 second) in carriers of the A allele.
Reference-Allele Phenotype
Normal MLLT3 function at this locus, associated with typical pharmacological response to montelukast in asthma management.
Evidence Level
3 — Limited — single study or in-vitro See methodology for how we grade evidence.
Cross-References
Informational only
This page summarizes population-level evidence about a genetic variant. It is not a diagnosis. Your individual risk depends on your full genome, lifestyle, environment, and family history. Consult a healthcare provider for personalized medical advice.
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