AncestryEvidence 1A

rs4988235 · MCM6

Risk allele: A

Risk-Allele Phenotype

Derived allele enables lactase persistence into adulthood; highly informative for European and pastoral ancestry.

Reference-Allele Phenotype

Ancestral allele (G) results in lactase non-persistence after childhood.

Evidence Level

1A — Strong — multiple high-quality studies See methodology for how we grade evidence.

Cross-References

dbSNP — rs4988235
ClinVar — search rs4988235
NCBI Gene — MCM6

Informational only

This page summarizes population-level evidence about a genetic variant. It is not a diagnosis. Your individual risk depends on your full genome, lifestyle, environment, and family history. Consult a healthcare provider for personalized medical advice.

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