PharmacogenomicsEvidence 1A

rs3892097 · CYP2D6

Risk allele: G

Risk-Allele Phenotype

CYP2D6*41 variant; intermediate metabolizer status; partial loss of CYP2D6 activity; reduced metabolism of antipsychotics, codeine, venlafaxine.

Reference-Allele Phenotype

Normal CYP2D6 function.

Evidence Level

1A — Strong — multiple high-quality studies See methodology for how we grade evidence.

Cross-References

dbSNP — rs3892097
ClinVar — search rs3892097
NCBI Gene — CYP2D6
PharmGKB — rs3892097

Informational only

This page summarizes population-level evidence about a genetic variant. It is not a diagnosis. Your individual risk depends on your full genome, lifestyle, environment, and family history. Consult a healthcare provider for personalized medical advice.

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