rs12248560 · CYP2C19
Risk allele: T
Risk-Allele Phenotype
CYP2C19 rs12248560 — associated with increased CYP2C19 enzyme function, leading to enhanced metabolism of clopidogrel to its active form and potentially altered antiplatelet efficacy and bleeding risk.
Reference-Allele Phenotype
Normal CYP2C19 metabolizer function at this locus, associated with standard clopidogrel activation and expected antiplatelet response.
Evidence Level
4 — Preliminary See methodology for how we grade evidence.
Cross-References
Informational only
This page summarizes population-level evidence about a genetic variant. It is not a diagnosis. Your individual risk depends on your full genome, lifestyle, environment, and family history. Consult a healthcare provider for personalized medical advice.
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