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AllergiesEvidence 1B

rs11059570 · HNMT

Risk allele: C

Risk-Allele Phenotype

Histamine N-methyltransferase C314T; C allele reduces HNMT activity and impairs histamine clearance.

Reference-Allele Phenotype

Ancestral allele (T) efficient histamine metabolism.

Evidence Level

1BStrong — single high-quality study See methodology for how we grade evidence.

Cross-References

Informational only

This page summarizes population-level evidence about a genetic variant. It is not a diagnosis. Your individual risk depends on your full genome, lifestyle, environment, and family history. Consult a healthcare provider for personalized medical advice.

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