CardiovascularhypertensionEvidence 2A

rs1057910 · CYP2C9

Risk-Allele Phenotype

CYP2C9 rs1057910 — associated with altered drug response related to irbesartan — Essential hypertension. This variant may influence medication efficacy or adverse reaction risk.

Reference-Allele Phenotype

Normal CYP2C9 function at this locus, with no elevated genetic risk contribution to irbesartan — Essential hypertension from this variant.

Evidence Level

2A — Moderate — meta-analysis See methodology for how we grade evidence.

Cross-References

dbSNP — rs1057910
ClinVar — search rs1057910
NCBI Gene — CYP2C9

Informational only

This page summarizes population-level evidence about a genetic variant. It is not a diagnosis. Your individual risk depends on your full genome, lifestyle, environment, and family history. Consult a healthcare provider for personalized medical advice.

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